Clinical Studies Find sam® Developed by ZetrOZ Systems Effectively Treats Osteoarthritis

Apr 6, 2021

Review finds ZetrOZ technology also lowers treatment costs significantly improving care for the aging patient population



TRUMBULL, Conn. - April 6, 2021 - (Newswire.com)

ZetrOZ Systems, a leading medical device manufacturer and sustained acoustic medicine pipeline development company, announces that a series of studies from 2014 through 2020 found that its sam® (sustained acoustic medicine) technology reduces pain and improves joint function in patients with knee osteoarthritis. In addition, studies show that sam® can cut the overall cost of treatment in half, by $27,000 on average, and reduce lost work time.

"Multiple clinical trials show that the ZetrOZ sam® technology not only is better at reducing patients' pain, but also saves patients, physicians and insurers time and money," said Dr. George Lewis, biomedical engineer and founder of ZetrOZ Systems. "It's a win-win for everyone involved."

In 2020, researchers examined the use of sustained acoustic medicine and ultrasound gel to treat 32 patients with moderate to severe pain from knee osteoarthritis. The study, in Open Orthopaedics Journal, found the treatment, four hours a day for one week, reduced pain from 50 to 70 percent across all patients.

"Sustained Acoustic Medicine combined with 1% topical diclofenac rapidly reduced pain and improved function in patients with moderate to severe osteoarthritis-related knee pain," the researchers wrote. The clinical findings suggest that this treatment approach may be used as a conservative, non-invasive treatment option for patients with knee osteoarthritis.

In a  2018 double-blind, placebo-controlled clinical study reported in the Journal of Orthopaedic Surgery and Research, 90 patients with knee osteoarthritis received four hours of sustained acoustic medicine treatment for six weeks. Patients receiving the treatment reported roughly twice as much reduction in pain and twice as much improved function as those receiving only a placebo. "Long-duration low-intensity ultrasound significantly reduced pain and improved joint function in patients with moderate to severe osteoarthritis knee pain," the authors wrote. 

Treatment with the ZetrOZ SAM device cost $4,400 for the four weeks, half the cost of other ultrasound treatments, the study reported. Another study, by the Institute for Clinical and Economic Review, found SAM treatment lowers cost by $27,000 on average and reduces lost work time, getting patients back to work more quickly. 

Clinical studies conducted in 2014 and 2015 had similar results. The 2015 study also found that SAM treatments reduced knee osteoarthritis pain twice as much as the placebo, while the 2014 pilot study found SAM reduced pain by 52 percent and improved mobility by 20 percent.

To learn more about ZetrOZ Systems and sam®, the company's long duration daily ultrasound treatment that reduces the need for pain medication and surgery, please visit http://www.zetroz.com. 

About ZetrOZ Systems:

ZetrOZ Systems is an FDA cGMP and ISO 13585 medical technology company headquartered in the southern coastal region of Connecticut. The organization also has manufacturing facilities across the United States. ZetrOZ Systems produced UltrOZ®, sam®Sport and sam®Pro 2.0 to provide safe and effective treatment options for prevalent conditions such as arthritis. Learn more at zetroz.com and samrecover.com.

Media Contact: 
Ledora Brown
[email protected]
www.Newswire.com




Press Release Service by Newswire.com

Original Source: Clinical Studies Find sam® Developed by ZetrOZ Systems Effectively Treats Osteoarthritis

More News

What do we know about Elizabeth Holmes’ brother, Christian, who’s not in You Can See Everything?
Oct 30, 2026
What do we know about Elizabeth Holmes’ brother, Christian, who’s not in You Can See Everything?

Elizabeth Holmes is back in the spotlight, thanks to Nathan Fielder and Lance Oppenheim’s hit new documentary, You Can See Everything (2026). Since its release on October 16, the film has proven a massive box office success, grossing over US$45 million worldwide. The film, which follows the disgraced Theranos founder, 42, and her long-time partner, Billy Evans, 34, during the days leading up to her imprisonment for criminal fraud, also features her parents, Christian and Noel Anne Holmes. Her...

How to have the best Sunday in L.A., according to Judy Reyes
Oct 30, 2026
How to have the best Sunday in L.A., according to Judy Reyes

New York-style bagels, a fresh manicure and a massage in the back of a sushi restaurant are on the agenda for the 'Scrubs' actor.

Hong Kong Disneyland Brings Halloween Treats to the Hong Kong Wine & Dine Festival
Oct 30, 2026
Hong Kong Disneyland Brings Halloween Treats to the Hong Kong Wine & Dine Festival

From October 29 to November 1, Hong Kong Disneyland Resort (HKDL) is participating in the annual “Hong Kong Wine & Dine Festival”, organized by the Hong Kong Tourism Board. For four consecutive days, HKDL will offer a selection of park-exclusive Halloween treats to the city, adding distinctive Disney storytelling and creativity to Hong Kong’s mega event tourism experience. Visitors can embrace the Disney Halloween spirit in the city before joining HKDL’s Booonus Wicked Night Party on October 30 and 31 for one last chance to enjoy the ultimate Halloween celebration.

Hotel Review: Faena, New York – Theatrical Design in West Chelsea
Oct 30, 2026
Hotel Review: Faena, New York – Theatrical Design in West Chelsea

New York's Chelsea strikes gold with this daring brand The post Hotel Review: Faena, New York – Theatrical Design in West Chelsea appeared first on Business Traveller.

Uncovering Madrid: discover the beat of a destination that extends well beyond the city centre
Oct 30, 2026
Uncovering Madrid: discover the beat of a destination that extends well beyond the city centre

[The content of this article has been produced by our advertising partner.] Madrid may be known as a city destination, but beyond its immediate hub there is much to embrace, taste and live. Europe’s beating heart deserves its unspoken, vibrant pulse to be felt, and its rhythm to course through the soul. For the discerning global traveller, Madrid unfolds, layer upon layer, to reveal a choreography of culture, heritage and modern indulgence. Time must be spent here to explore, discover,...

12 new Hong Kong restaurants, bars and cafes to visit in November 2026
Oct 30, 2026
12 new Hong Kong restaurants, bars and cafes to visit in November 2026

Hong Kong welcomes a wave of new restaurants in November, including several international debuts. Food lovers can look forward to the relocation of a popular French concept, a premium hotpot joint with exclusive recipes, and much more. Hong Kong’s cafe scene also has some new additions, including a viral bakery from overseas and a Japanese pastry collaboration. There are also some innovative multi-concept bars that aim to redefine Hong Kong nightlife. Read on to discover more. 1. Bar...

Transylvania, Where Meadows Ripple and Dracula Legends Fade
Oct 30, 2026
Transylvania, Where Meadows Ripple and Dracula Legends Fade

On a three-day hike in Romania, a writer sidesteps the usual Bram Stoker draws and instead discovers medieval villages, ancient forests and rich living history.

Tourism Authority of Thailand Launches ‘Gateway to Thailand Travel Guidebook’
Oct 30, 2026
Tourism Authority of Thailand Launches ‘Gateway to Thailand Travel Guidebook’

Crossing the border is never about passing a checkpoint; it marks the true beginning of discovering Thailand. Recognizing this potential, the Tourism Authority of Thailand (TAT) introduced the ‘Gateway to Thailand’ travel guide, inviting overland travelers to journey far beyond the entry gates along ten curated road trips connecting vibrant cities, iconic attractions, and local communities across the nation.

LGBT+ Tourism Could Generate US$521 Billion by 2031
Oct 30, 2026
LGBT+ Tourism Could Generate US$521 Billion by 2031

LGBT+ tourism is becoming increasingly important to the global economy, but challenges related to safety and welcoming environments continue to directly influence travel decisions among this audience. Valued at US 311 billionin 2024, the marketis projected to reach US5 21 billion by 2031, according to data from Grand View Research compiled in the special PANROTAS LGBTravel 2026 edition. In Brazil, a survey presented in September during the 10th International Diversity Conference, organized by the Brazilian LGBT+ Chamber of Commerce and Tourism, helps shed light on these travel behaviors.

Brand USA Reveals the Can’t-Miss Holiday Celebrations in America
Oct 30, 2026
Brand USA Reveals the Can’t-Miss Holiday Celebrations in America

Tis the season to be jolly, and throughout the USA, cities large and small are hauling out the holly and decking their halls as they prepare to celebrate the holiday season. From the 100th anniversary of the Macy’s Thanksgiving Day Parade to countless twinkling holiday light shows to New Year’s Eve drops unlike any you’ve seen before, you’ll find a variety of ways to ring in Thanksgiving, Hanukkah, Christmas, Kwanzaa and New Year’s.

Tokyo and Around Tokyo: Discover Nikko’s Autumn Colours by Rail
Oct 30, 2026
Tokyo and Around Tokyo: Discover Nikko’s Autumn Colours by Rail

Autumn is one of the most beautiful times to explore Nikko, where colourful foliage transforms the mountains, lakes and historic sites north of Tokyo. With autumn colours gradually spreading from the higher elevations of Oku-Nikko to the city centre, visitors can enjoy seasonal scenery over several weeks. Combining spectacular natural landscapes with UNESCO World Heritage sites and convenient rail connections from Tokyo, Nikko is an appealing addition to an autumn itinerary in Japan.

Britain’s Bank of Grandparents is Reshaping the Luxury Ski Holiday, with VIP SKI
Oct 30, 2026
Britain’s Bank of Grandparents is Reshaping the Luxury Ski Holiday, with VIP SKI

Booming over-65 spending is fuelling this and the trend mirrors wider consumer spending patterns. Economic analysis from Barclays Insights in 2026 reveals that travel spending by the over-65 demographic grew by 6.8%, outperforming all other age groups. This generation is heavily financing large-scale family holidays and are Britain’s fastest-growing travel spenders.

YOUR NEWS, OUR NETWORK.

Do you have Great News you want to tell the world?

Be it updates about your business or your community, you can make sure that it’s heard by submitting your story to our network reaching hundreds of news sites across 6 verticals.

Life Ponds

Life Ponds publishes travel and lifestyle on a daily basis. We believe that Life Ponds will help to solve your problems every time you face a challenge.

Newsletter