Green Park Collaborative and Allergy & Asthma Network Publish a Core Outcome Set for Clinical Trials in Moderate to Severe Asthma
Apr 6, 2021
BALTIMORE, April 6, 2021 /PRNewswire/ -- The Green Park Collaborative (GPC), a major initiative of the Center for Medical Technology Policy (CMTP), in partnership with Allergy & Asthma Network (AAN), led a stakeholder consensus initiative to recommend outcomes that should be core across all phase 3 and 4 clinical drug trials for moderate to severe asthma.
The report, published in the Annals of Allergy, Asthma and Immunology, describes the multi-stakeholder consensus process used to prioritize nearly 100 outcomes down to a final set of five core outcomes. Participants represented many perspectives, including patients, clinicians, researchers, payers, health technology assessors, regulators, and drug development companies.
"The coreASTHMA core outcome set is a triumph. Even in a condition like asthma, where the most important outcomes for clinical research might seem self-evident, valuable insights on outcome selection were gained through multistakeholder engagement. I am confident that as these insights are adopted into clinical research, producing more relevant data consistently, patients will be the ultimate winners," says Donna Messner, President & CEO, CMTP.
With many recently approved and additional emerging therapies in asthma, outcomes used in trials are heterogenous — creating challenges for drawing meaningful comparisons between these therapies. "Consistent inclusion of these outcomes will allow comparison across trials to provide further guidance on benefits of one therapeutic option versus another," says Vickram Tejwani, Pulmonary and Critical Care Fellow, Johns Hopkins Hospital.
Furthering their partnership, CMTP and AAN have also launched a follow-up initiative called coreASTHMA QoL to build upon the insight gained from coreASTHMA that current asthma-specific quality of life measures do not readily translate into meaningful improvements in patients' lives. "The coreASTHMA project highlighted that asthma-specific quality of life is an important outcome to patients. In coreASTHMA QoL, we will ensure this outcome is measured in a way that is relevant to how patients perceive quality of life," says Tonya Winders, President & CEO, AAN.
About the Green Park Collaborative (GPC)
GPC is a major initiative of CMTP, an independent 501(c)(3) non-profit organization dedicated to improving the quality, relevance, and efficiency of clinical research. GPC is a multi-stakeholder forum for developing condition-and technology-specific study design recommendations to guide the creation of evidence needed to inform both clinical and payment decisions.
About Allergy & Asthma Network (AAN)
AAN is the leading nonprofit patient education and advocacy organization for people with asthma, allergies, and related conditions. AAN's patient-centered network unites individuals, families, healthcare professionals, industry, and government decision makers to improve health and quality of life for Americans with asthma and allergies. We specialize in making accurate medical information relevant and understandable to all while promoting evidence-based standards of care.
Contact
Green Park Collaborative
Aisha Robinson
410-547-2687 ext. 114
[email protected]
More News
Hotel Review: Mount Juliet Estate, County Kilkenny
Fresh from an extensive refurbishment, Mount Juliet Estate pairs Georgian character with Michelin-starred dining, championship golf, attentive service and an extraordinary roster of country pursuits across 500 acres in Kilkenny. The post Hotel Review: Mount Juliet Estate, County Kilkenny appeared first on Business Traveller.
American Express Platinum Adds Airbnb Luxe to $600 Lodging Credit
Amex Platinum is venturing beyond hotels. Airbnb Luxe now qualifies for its $600 lodging credit, while a new $250 Experiences benefit sweetens the deal—but one-night FHR stays are losing ground. The post American Express Platinum Adds Airbnb Luxe to $600 Lodging Credit appeared first on Business Traveller.
Hotel Review: The Brazilian Court, Palm Beach
Celebrating its centennial, The Brazilian Court pairs secluded courtyards, residential-style suites and Café Boulud with one of Palm Beach’s best locations, delivering old-world character without feeling frozen in time. The post Hotel Review: The Brazilian Court, Palm Beach appeared first on Business Traveller.
Meet the Judges: Business Traveller Awards 2026
Our global awards were shaped by a panel of experts across the travel, media, design and hospitality industries The post Meet the Judges: Business Traveller Awards 2026 appeared first on Business Traveller.
United Opens Its Largest Airport Lounge in Houston Terminal B
Airport lounges keep getting bigger, and United may have just won the square-footage contest. Houston’s new 54,000-square-foot club seats 800—assuming the crowds do not arrive faster than the furniture. The post United Opens Its Largest Airport Lounge in Houston Terminal B appeared first on Business Traveller.
1st human case of livestock virus Shamonda reported in France
France on Thursday reported the first human case of the Shamonda virus usually found in livestock in a patient who later died, with authorities adding there was no risk to the general population at this stage.
Turkish Airlines Chairman Murat Şeker on Premium, Personalisation and the Path to the Top Three
Turkish Airlines has conquered scale. Now it’s setting its sights on a distinctive guest experience. The post Turkish Airlines Chairman Murat Şeker on Premium, Personalisation and the Path to the Top Three appeared first on Business Traveller.
Help! Why Won’t Travel Insurance Pay for My $17,500 Broken Leg?
An American tourist had emergency surgery in Thailand after tripping and falling at an ice cream counter. Good thing he bought insurance — or so it seemed.
Long COVID patients 'devastated' by impending changes to virtual care access in B.C.
More than 300,000 British Columbians live with long COVID, with many relying on virtual appointments to access the care they need. But health providers are warning impending caps on appointment sizes and changes to fees will create lengthy delays and lead to cutbacks in vital programs.
Vanessa Branson on Her Travel Hacks, Essentials and Favourite Trips
Vanessa Branson has all the hacks from years of international travel. Her top tip? Screenshot everything. The post Vanessa Branson on Her Travel Hacks, Essentials and Favourite Trips appeared first on Business Traveller.
HBO Max K-drama Make Me Tingle: Nam Ji-hyun, Kim Jae-young lead tame sex romcom
Lead cast: Nam Ji-hyun, Kim Jae-young South Korea finds itself at an interesting juncture in its social evolution in the mid-2020s. Following the success of works such as the 2016 book Kim Ji-young, Born 1982 and its hit 2019 film adaptation, which brought the country’s gender inequality into sharp focus, the imbalance remains stubbornly stark. People now recognise this imbalance and are unafraid to label it for what it is – “patriarchy” is no longer a dirty word. Yet change has been slow. South...
YOUR NEWS, OUR NETWORK.
Do you have Great News you want to tell the world?
Be it updates about your business or your community, you can make sure that it’s heard by submitting your story to our network reaching hundreds of news sites across 6 verticals.